Phospholipase C-related but Catalytically Inactive Protein (PRIP) Modulates Synaptosomal-associated Protein 25 (SNAP-25) Phosphorylation and Exocytosis*
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چکیده
منابع مشابه
- 1 - Phospholipase C - related , but catalytically inactive protein PRIP modulates SNAP - 25 phosphorylation and exocytosis
Background: Phospho-modulation of SNARE function has not yet known. Results: Phospho-SNAP-25 was de-phosphorylated by protein phosphatase-1 whose activity was regulated by PRIP, thus regulating exocytosis. Conclusion: Protein phosphatase-1 whose activity is regulated by PRIP, is the major phosphatase responsible for the de-phosphorylation of SNAP-25. Significance: The results provide the first ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2012
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.294645